ERITROMITSIN-NIKA
ERITROMITSIN-NIKA

Инструкция по применению

Для специалистов здравоохранения

Indications


Bacterial infections caused by pathogens sensitive to erythromycin:


- Infections of ENT organs (laryngitis, pharyngitis, tonsillitis, sinusitis, external and middle otitis media);


- Lower respiratory tract infections (tracheitis, bronchitis, pneumonia);


- skin and soft tissue infections (pustular skin diseases, including infected wounds, bedsores, burns II-III st., trophic ulcers);


- biliary tract infections (cholecystitis);


- genitourinary infections in pregnant women caused by Chlamydia trachomatis;


- uncomplicated chlamydia in adults (with localization in the lower urinary tract and rectum) in case of intolerance or ineffectiveness of tetracyclines;


- primary syphilis (in patients allergic to penicillins);


- gonorrhea;


- scarlatina, legionellosis (Legionnaires' disease), listeriosis, trachoma;


- prevention of exacerbations of streptococcal infection (tonsillitis, pharyngitis) in patients with rheumatism.


- Prevention of infective endocarditis during dental interventions and operations on ENT organs in patients with risk factors (heart defects, prosthetic valves, etc.).


Erythromycin is a reserve antibiotic in case of allergy to penicillin and other antibiotics of the penicillin group, as well as to other beta-lactams.

Information on proper use 

How to use and dosage



Oral tablets. The medicine should be taken 1-2 hours before a meal or 2-3 hours after a meal. The tablets should be taken without chewing, without breaking, and with enough water.

Adults and adolescents over 14 years of age.

Single dose - 250-500 mg;

Daily dose - 1000-2000 mg (1-2 g).

Erythromycin is taken 4 times a day, the interval between doses - 6 hours. With a daily dose of erythromycin not more than 1 g - it is possible to use the drug in 2 doses (500 mg every 12 hours). In severe infections the daily dose of erythromycin can be increased up to 4 g (4000 mg).

Maximum daily dose: 4 g (4000 mg).

The course of treatment is 5-14 days, after the disappearance of symptoms, treatment is continued for 2 more days.

Treatment of streptococcal infections of various localizations (including tonsillopharyngitis): should last at least 10 days.

In juvenile acne: 250 mg 2 times a day simultaneously with topical therapy, then after 1 month from the beginning of treatment, depending on the condition, the dose can be reduced to 250 mg once a day.

In uncomplicated chlamydia (urethral, endocervical or rectal) with intolerance to tetracycline antibiotics: 500 mg 4 times a day for at least 7 days.

Treatment of primary syphilis: course dose is equal to 30-40 g, duration of treatment is 10-15 days, frequency of administration - 4 times a day. It is preferable to start treatment with intravenous administration, with subsequent transition to oral forms.

In gonorrhea: 500 mg g every 6 hours for 3 days, then 250 mg every 6 hours for 7 days.

Treatment of diphtheria bacteremia: 250 mg 2 times a day for at least 7 days.

In whooping cough: 100-250 mg 4 times a day, course of treatment 5-14 days.

In scarlatina: treatment course - at least 10 days.

In legionellosis (legionnaires' disease): daily dose 2-4 g divided into 4 doses (500-1000 mg 4 times a day) until disappearance of clinical symptoms of the disease (but not less than 14 days).

In listeriosis: 250-500 mg 4 times a day for at least 7 days, etiotropic therapy is carried out until the 6th-7th day of normal temperature, and in severe forms - until the 14th-21st day.

In erythrasma: 250 mg 4 times a day for 5-7 days simultaneously with external agents.

In amoebic dysentery: 250 mg 4 times a day. Duration of treatment - 10-14 days.

Prevention of exacerbations of streptococcal infection (tonsillitis, pharyngitis) in patients with rheumatism: 250-500 mg 4 times a day, course duration - at least 10 days.

Prevention of infective endocarditis in patients with heart defects in dental interventions and operations on ENT organs - adults 1 g (1000 mg) 1-2 hours before therapeutic or diagnostic procedures, then 500 mg every 6 hours, a total of 8 receptions.

Children from 6 to 14 years old.

Depending on age, body weight and severity of infection - 30-50 mg/kg per day in 2-4 doses. In case of severe infections, the dose may be doubled.                                                           

For prophylaxis of streptococcal infection (in tonsillitis, pharyngitis): 20-30 mg/kg/ per day, course duration - at least 10 days.                                                            

For prophylaxis of septic endocarditis in patients with heart defects: 20 mg / kg 1 hour before the treatment or diagnostic procedure, then 10 mg / kg, repeated after 6 hours.

For pneumonia in children: 50 mg/kg per day in 4 doses, for at least 3 weeks.