Omeprazolponizhiruet secretion of hydrochloric acid from parietal cells by inhibition of the H +, K + -ATPase proton pump, an enzyme that catalyzes the final stage of hydrochloric acid secretion., catalyzing the final stage of hydrochloric acid secretionIn this case, the drug promotes inhibition of both basic and stimulated (regardless of the nature of the stimulus) acid secretion . Inhibition of acid secretion after a single dose continues for 24-72 hours. When discontinuation of the drug secretory activity gradually returns to the initial 3-5 days later. Does not inhibit the secretion of pepsin, increases the serum level of gastrin, which returns to the initial value, usually within 1-2 weeks after discontinuation of therapy with the drug.
Indications for use
Prevention and treatment of gastric and duodenal ulcers, including resistant to H2 receptor antagonists, Erosive-ulcerative lesions caused by non-steroidal anti-inflammatory drugs, reflux esophagitis, Zollinger-Ellison syndrome. Destruction of Helicobacter pylori (in combination with antibiotics) in patients suffering from gastric ulcer and duodenal ulcer.
There are contraindications, before use, consult with the doctor!